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Mice were subjected to 90 min middle cerebral artery occlusion. CD47 knockout mi … lnc-CD47-10: RNA Gene: 4: GC03M107935: 6.73: 14: RHD: Rh Blood Group D Antigen: Protein Coding: 42: GC01P025272: 6.30: 15: LINC00636: Long Intergenic Non-Protein Coding RNA 636: RNA Gene: 17: GC03P107883: 6.26: 16: PTPN11: Protein Tyrosine Phosphatase Non-Receptor Type 11: Protein Coding: 54: GC12P112418: 6.22: 17: CD44: CD44 Molecule (Indian Blood Group) Protein Coding: 48: GC11P035139: 6.10: 18: ENSG00000279277 CD47 (CD47 molecule) is a protein-coding gene. Diseases associated with CD47 include neonatal meningitis . GO annotations related to this gene include thrombospondin receptor activity . 2021-01-14 · DQ893920 - Synthetic construct Homo sapiens clone IMAGE:100008380; FLH165697.01L; RZPDo839F08159D CD47 molecule (CD47) gene, encodes complete protein. AB590342 - Synthetic construct DNA, clone: pFN21AE1472, Homo sapiens CD47 gene for CD47 molecule, without stop codon, in Flexi system.
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The 2 Nov 2018 CD47 Blockade by Hu5F9-G4 and Rituximab in Non-Hodgkin's Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia. 7 Mar 2013 The passport is based on a protein found on nearly all mammalian cell membranes, CD47, which is known as a marker of "self." While the Dr Naval Daver speaks to ecancer in an online interview for the virtual EHA 2020 meeting. He describes the background, study design and results of this. 29 Nov 2017 When CD47 binds to a protein called SIRPalpha on the surface of macrophages, a “don't eat me” signal is triggered and the macrophage ignores CD47 (Cluster of Differentiation 47) also known as integrin associated protein ( IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 is a potent “don't eat me” signal that enables cancer cells to evade immune surveillance and killing by innate immune cells, such as macrophages. L-DOS47 is an antibody protein conjugate where the urease component enzymatically converts naturally occurring urea to ammonia. The L-DOS47 drug Cell & Gene Therapy · Cell-based Immunotherapy · HLA Typed Cells · Protein & Vaccine Production · Mammalian Protein Expression · Vaccine Manufacturing.
Made to Order. Catalog # 4390771 Standard | 5 nmol : … CD47 blockade triggers T cell–mediated destruction of immunogenic tumors. Nature medicine, 2015, 21(10): 1209-1215.
Gene: CD47; CD47 molecule: Aliases: IAP, OA3, MER6 : Location: 3q13.12: Summary: This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. CD47 (integrin-associated protein, IAP) is a ubiquitously expressed cell surface transmembrane glycoprotein interacting with several integrins and regulating their functions.
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CD47 (C luster of D ifferentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene. CD47 belongs to the immunoglobulin superfamily and partners with membrane integrins and also binds the ligands thrombospondin-1 (TSP-1) and signal-regulatory protein alpha (SIRPα). gene Summary CD47 - CD47 molecule (human) CD47 (CD47 Molecule) is a Protein Coding gene. Diseases associated with CD47 include Hereditary Spherocytosis and Neonatal Meningitis. Among its related pathways are Integrin Pathway and Cell surface interactions at the vascular wall. Gene Ontology (GO) annotations related to this gene include thrombospondin receptor activity. Among the various candidate genes involved in acute rejection, CD47 inhibits monocyte/macrophage-mediated phagocytosis by identifying the CD47 signal regulatory protein alpha (SIRP-alpha) as self/non-self.
Antibody staining with HPA044659 and CAB016055 in immunohistochemistry.
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Gene WT_Nondiff_2_Control_vs_WT_Nondiff_1_Control-FC 0.15 -2.2 8e-04 0.0054 Cd47 0.13 0.14 0.44 -0.75 0.0059 0.071 -0.88 0.0053 0.012 1.4 0.00048 Proteinerna CD47 och SIRP?
Cd47 Gene Detail Summary Symbol. Cd47 Name. CD47 antigen (Rh-related antigen, integrin-associated signal transducer) Synonyms.
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Defects in CD4+ T cell LFA-1 integrin-dependent adhesion
This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occu rs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction.
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Together, these findings identified a macrophage MIAT/miR-149-5p /CD47 pathway as a key factor in the development of Gene Knockdown Techniques. molecular biology techniques to provide evidence demonstrating the transcription factor alpha-Pal/NRF-1 is a critical regulator of the human IAP/CD47 gene. Blocking cd47/ox101 makes the astrocytes permissive for nerve fiber growth2011Ingår i: Glia: 10th European meeting on Glial Cells in Health and Disease, New Regulates Iap/Cd47 Expression and Neurite Outgrowth in Neurons: Huang, factor alpha-Pal/NRF-1 is a critical regulator of the human IAP/CD47 gene. Gene Symbol, Annotation, Raw Average WT Counts, Converted WT1 TPM, Converted Cd47, CD47 antigen (Rh-related antigen, integrin-associated signal 52, RP11-74C13.3, Normalizer. 53, COG1, Normalizer. 54, CD47, Normalizer.
Go to complete Gene record for CD47; … CD47 is a cell surface glycoprotein that helps mediate neutrophil transmigration across blood vessels. The present study was performed to determine whether absence of the CD47 gene decreases focal ischemic brain damage. Mice were subjected to 90 min middle cerebral artery occlusion. CD47 knockout mice were compared against matching wildtype mice. CD47 (IAP, MER6, OA3) protein expression summary. This gene encodes a membrane protein, which is involved in the increase in intracellular calcium concentration that occu rs upon cell adhesion to extracellular matrix.